1-بوتانول 100988 مرک

Product Information
CAS number	71-36-3
EC index number	603-004-00-6
EC number	200-751-6
Grade	NF
Hill Formula	C₄H₁₀O
Chemical formula	CH₃(CH₂)₃OH
Molar Mass	74.12 g/mol
HS Code	2905 13 00
Structure formula Image

Applications
Application	1-Butanol suitable for use as excipient EMPROVE® exp NF. CAS 71-36-3, chemical formula CH₃(CH₂)₃OH.

Physicochemical Information
Boiling point	116 - 118 °C (1013 hPa)
Density	0.81 g/cm3 (20 °C)
Explosion limit	1.4 - 11.3 %(V)
Flash point	34 °C
Ignition temperature	340 °C
Melting Point	-89 °C
pH value	7 (70 g/l, H₂O, 20 °C)
Vapor pressure	6.7 hPa (20 °C)
Solubility	66 g/l

Toxicological Information
LD 50 oral	LD50 Rat 790 mg/kg
LD 50 dermal	LD50 Rabbit 3400 mg/kg

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H226: Flammable liquid and vapour. H302: Harmful if swallowed. H315: Causes skin irritation. H318: Causes serious eye damage. H335: May cause respiratory irritation. H336: May cause drowsiness or dizziness.
Precautionary Statement(s)	P210: Keep away from heat. P280: Wear eye protection. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P313: Get medical advice/ attention.
RTECS	EO1400000
Storage class	3 Flammable liquids
WGK	WGK 1 slightly water endangering
Disposal	1 Strongly contaminated halogen-free organic solvents: container A.

Safety Information
Hazard Symbols	Harmful
Categories of danger	flammable, harmful, irritant
R Phrase	R 10-22-37/38-41-67 Flammable.Harmful if swallowed.Irritating to respiratory system and skin.Risk of serious damage to eyes.Vapours may cause drowsiness and dizziness.
S Phrase	S 7/9-13-26-37/39-46 Keep container tightly closed and in a well-ventilated place.Keep away from food, drink and animal feedingstuffs.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable gloves and eye/face protection.If swallowed, seek medical advice immediately and show this container or label.

Storage and Shipping Information
Storage	Store at +5°C to +30°C.

Transport Information
Declaration (railroad and road) ADR, RID	UN 1120 , 3, III
Declaration (transport by air) IATA-DGR	UN 1120 , 3, III
Declaration (transport by sea) IMDG-Code	UN 1120 , 3, III

Specifications
Purity (GC)	≥ 99.5 %
Identity (IR)	conforms
Identity (B)	conforms
Acidity	conforms
Limit of Butyraldehyde, 2-Butanol, Isobutyl alcohol and Butyl ether (GC)	conforms
Butyraldehyde (GC)	≤ 0.1 % (v/v)
2-Butanol (GC)	≤ 0.1 % (v/v)
2-Methylpropan-1-ol (GC)	≤ 0.1 % (v/v)
Butyl ether (GC)	≤ 0.2 % (v/v)
Residual solvents class 3 (ICH Q3C)	< 0,5 %
Other residual solvents (ICH Q3C)	excluded by production process
Evaporation residue	≤ 0.0040 %
Water	≤ 0.10 %
Residue of metal catalysts or metal reagents according to EMEA/CHMP/SWP/4446/2000 are not likely present. Conforms to NF